En gruppe lidelser og tilstander i hjernen som kan forårsake funksjonsforstyrrelser som karakteriseres av ulike previous av anfall, enten med eller uten innvirkning på bevisstheten, og med eller uten krampeanfall.
Slutt å bruke dette legemidlet og snakk med lege med en gang dersom Du får plutselig pustevansker eller gispende pust eller hevelser i ansikt, munn eller svelg.
Serotonin: Modafinil is known to improve levels of serotonin, a neurotransmitter vital for regulating mood by stimulating the serotonergic system during the cortex, hypothalamus, and amygdala.
It is additionally useful for folks whose Work require them to generally be notify and Lively at nighttime when their circadian clocks are telling them to snooze.
acetazolamide will improve the degree or outcome of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Unfamiliar.
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Having said that, scientific tests suggest that it blocks the norepinephrine transporter or Internet in much the exact same way that it blocks the dopamine transporter, Hence expanding the quantity of straight away offered norepinephrine.[32]
fedratinib will enhance the degree or result of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of. Alter dose get more info of medicines which might be CYP3A4 substrates as vital.
For anyone who is using modafinil to treat sleepiness attributable to obstructive rest apnea, you may also be treated having a continuous good airway stress (CPAP) machine.
Despite the fact that only one study with major constraints tested the effects of modafinil on humor appreciation (Killgore et al 2006), this subject deserves distinct focus, simply because humor appreciation is a very elaborate neural task requiring frontal lobe purpose and integrative information processing involving quite a few cortical and subcortical brain locations (Shammi and Stuss 1999; Goel and Dolan 2001; Mobbs et al 2003; Moran et al 2004). This take a look at as opposed the results of modafinil to caffeine and amphetamine in not only humor appreciation, but additionally PVT effectiveness and Stanford Sleepiness Exam Rating.
Belzutifan is often a CYP2C19 substrate. Coadministration with CYP2C19 inhibitors may raise incidence or severity of adverse consequences. Watch for anemia and hypoxia and reduce belzutifan dose as proposed.
Threat of skin reactions, Steven-Johnsons Syndrome, poisonous necrolysis, and drug rash with eosinophilia and systemic indicators; discontinue if rash or other hypersensitivity reactions occur
If you think There's been an overdose, phone your poison Management Heart or get medical treatment at once. Be ready to explain to or exhibit what was taken, the amount of, and when it occurred.
sparsentan will reduce the extent or influence of modafinil by affecting hepatic enzyme CYP2C19 metabolism. Use Caution/Keep track of. Sparsentan (a CYP2C19 inducer) decreases exposure of CYP2C19 substrates and minimizes efficacy associated with these substrates.